Association of genetic variation of the transforming growth factor-alpha gene with cleft lip and palate.

Complex segregation analysis of pedigrees having nonsyndromic cleft lip with or without cleft palate (CL/P) (Chung et al. 1986; Marazita et al. 1986) has shown that a major-locus model best explains the observed recurrence of CL/P in Caucasian families. To identify this major gene, we compared the f...

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Detalhes bibliográficos
Main Authors: Ardinger, H H, Buetow, K H, Bell, G I, Bardach, J, VanDemark, D R, Murray, J C
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683414/
https://ncbi.nlm.nih.gov/pubmed/2570526
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