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3′ poly(A) is dispensable for translation

In wild-type cells, the 3′ poly(A) structure is necessary for translation of mRNA and for mRNA stability. The superkiller 2 (ski2), ski3, ski6, ski7, and ski8 mutations enhance the expression of the poly(A)(−) mRNAs of yeast RNA viruses. Ski2p is a DEVH-box RNA helicase and Slh1p resembles Ski2p. Bo...

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Bibliografske podrobnosti
Main Authors: Searfoss, Anjanette M., Wickner, Reed B.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC16834/
https://ncbi.nlm.nih.gov/pubmed/10922069
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