Population variation of human mtDNA control region sequences detected by enzymatic amplification and sequence-specific oligonucleotide probes.

A method for detecting sequence variation of hypervariable segments of the mtDNA control region was developed. The technique uses hybridization of sequence-specific oligonucleotide (SSO) probes to DNA sequences that have been amplified by PCR. The nucleotide sequences of the two hypervariable segmen...

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Detalles Bibliográficos
Autores principales: Stoneking, M, Hedgecock, D, Higuchi, R G, Vigilant, L, Erlich, H A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1991
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683035/
https://ncbi.nlm.nih.gov/pubmed/1990843
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