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Human CYP1A1 gene: cosegregation of the enzyme inducibility phenotype and an RFLP.

The human CYP1A1 (cytochrome P1450) gene encodes an enzyme involved in the activation of procarcinogens, such as benzo[a]pyrene, to the ultimate reactive intermediate. Approximately 10% of the human population exhibit high CYP1A1 inducibility, and Kouri et al. reported that the high-inducibility phe...

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Detalhes bibliográficos
Main Authors: Petersen, D D, McKinney, C E, Ikeya, K, Smith, H H, Bale, A E, McBride, O W, Nebert, D W
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682951/
https://ncbi.nlm.nih.gov/pubmed/1707592
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