A t(4;22) in a meningioma points to the localization of a putative tumor-suppressor gene.

Cytogenetic analysis of meningioma cells from one particular patient (MN32) displayed the stem-line karyo-type 45, XY, -1, 4p+, 22q-, 22q+, which thus had rearrangements of both chromosomes 22. The 22q+ marker appeared as a dicentric: 22 pter----q11::1p11----qter. The reciprocal product of this tran...

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Main Authors: Lekanne Deprez, R H, Groen, N A, van Biezen, N A, Hagemeijer, A, van Drunen, E, Koper, J W, Avezaat, C J, Bootsma, D, Zwarthoff, E C
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682947/
https://ncbi.nlm.nih.gov/pubmed/2014801
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