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Evidence for genetic heterogeneity in tuberous sclerosis: one locus on chromosome 9 and at least one locus elsewhere.

Linkage of tuberous sclerosis complex (TSC), an autosomal dominant disorder, to markers on chromosome 9 was reported first in 1987. This assignment was confirmed by an international collaborative study that suggested more than one locus may be responsible for the phenotype. We studied 14 multigenera...

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Detalhes bibliográficos
Main Authors: Northrup, H, Kwiatkowski, D J, Roach, E S, Dobyns, W B, Lewis, R A, Herman, G E, Rodriguez, E, Daiger, S P, Blanton, S H
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682771/
https://ncbi.nlm.nih.gov/pubmed/1415216
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