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Multicolor in situ hybridization and linkage analysis order Charcot-Marie-Tooth type I (CMTIA) gene-region markers.

This study demonstrates a clear and current role for multicolor in situ hybridization in expediting positional cloning studies of unknown disease genes. Nine polymorphic DNA cosmids have been mapped to eight ordered locations spanning the Charcot-Marie-Tooth type 1 (CMT1A) disease gene region in dis...

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Detalhes bibliográficos
Main Authors: Lebo, R V, Lynch, E D, Bird, T D, Golbus, M S, Barker, D F, O'Connell, P, Chance, P F
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682543/
https://ncbi.nlm.nih.gov/pubmed/1729894
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