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Conclusions of segregation analysis for family data generated under two-locus models.

Susceptibility to a disease may involve the interactive effect of two genes. What conclusions will be drawn by segregation analysis in such a case? To answer this question, we considered a set of two-locus models and the corresponding exact distribution for 300 families. We investigated the conclusi...

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Bibliographic Details
Main Authors: Dizier, M H, Bonaïti-Pellié, C, Clerget-Darpoux, F
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682497/
https://ncbi.nlm.nih.gov/pubmed/8250049
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