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An analysis of variation in expression of neurofibromatosis (NF) type 1 (NF1): evidence for modifying genes.

Neurofibromatosis (NF) type 1 (NF1) is notable for its variable expression. To determine whether variation in expression has an inherited component, we examined 175 individuals in 48 NF families, including six MZ twin pairs. Three quantitative traits were scored--number of café-au-lait patches, numb...

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Bibliografische gegevens
Hoofdauteurs: Easton, D F, Ponder, M A, Huson, S M, Ponder, B A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1993
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682337/
https://ncbi.nlm.nih.gov/pubmed/8328449
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