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Molecular etiology of low-penetrance retinoblastoma in two pedigrees.

In one family with low-penetrance retinoblastoma, a germ-line deletion is shared by affected and unaffected, obligate carriers. The deletion encompasses exon 4 of the retinoblastoma gene and corresponds to a mutant protein without residues 127-166. In a second family, RFLP analysis shows that two di...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Dryja, T P, Rapaport, J, McGee, T L, Nork, T M, Schwartz, T L
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1993
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682279/
https://ncbi.nlm.nih.gov/pubmed/8099255
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