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Imprinting of human H19: allele-specific CpG methylation, loss of the active allele in Wilms tumor, and potential for somatic allele switching.

Genomic imprinting and monoallelic gene expression appear to play a role in human genetic disease and tumorigenesis. The human H19 gene, at chromosome 11p15, has previously been shown to be monoallelically expressed. Since CpG methylation has been implicated in imprinting, we analyzed methylation of...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Zhang, Y, Shields, T, Crenshaw, T, Hao, Y, Moulton, T, Tycko, B
פורמט: Artigo
שפה:Inglês
יצא לאור: 1993
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682243/
https://ncbi.nlm.nih.gov/pubmed/8391213
תגים: הוספת תג
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