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Germ-line origins of mutation in families with hemophilia B: the sex ratio varies with the type of mutation.

Previous epidemiological and biochemical studies have generated conflicting estimates of the sex ratio of mutation. Direct genomic sequencing in combination with haplotype analysis extends previous analyses by allowing the precise mutation to be determined in a given family. From analysis of the fac...

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Detalhes bibliográficos
Main Authors: Ketterling, R P, Vielhaber, E, Bottema, C D, Schaid, D J, Cohen, M P, Sexauer, C L, Sommer, S S
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682121/
https://ncbi.nlm.nih.gov/pubmed/8434583
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