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Notch activity permits retinal cells to progress through multiple progenitor states and acquire a stem cell property

Signaling through the Notch pathway regulates multiple aspects of development. The vertebrate retina allows an investigation of the basis for these various effects, because the major cell types of the retina arise from a common progenitor that expresses Notch1. The Notch pathway was constitutively a...

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Detalhes bibliográficos
Main Authors: Jadhav, Ashutosh P., Cho, Seo-Hee, Cepko, Constance L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682012/
https://ncbi.nlm.nih.gov/pubmed/17148603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608155103
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