The NF-κB signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation

Atherosclerotic lesions form at distinct sites in the arterial tree, suggesting that hemodynamic forces influence the initiation of atherogenesis. If NF-κB plays a role in atherogenesis, then the activation of this signal transduction pathway in arterial endothelium should show topographic variation...

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Hlavní autoři: Hajra, Leena, Evans, Andrew I., Chen, Mian, Hyduk, Sharon J., Collins, Tucker, Cybulsky, Myron I.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2000
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC16820/
https://ncbi.nlm.nih.gov/pubmed/10922059
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