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BRCA1 and BRCA2 Pathways and the Risk of Cancers Other Than Breast or Ovarian
ABSTRACT: OBJECTIVE: Germline mutations in the tumor suppressor genes BRCA1 and BRCA2 predispose women to breast and ovarian cancer. Female carriers of BRCA1 or BRCA2 gene mutations have very high lifetime risks for breast and ovarian cancers. Genetic abnormalities occur in all cancers, so BRCA-rela...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Medscape
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1681605/ https://ncbi.nlm.nih.gov/pubmed/16369438 |
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