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OLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in concert with LMO1.

OLIG2 (originally designated BHLHB1) encodes a transcription factor that contains the basic helix-loop-helix motif. Although expression of OLIG2 is normally restricted to neural tissues, overexpression of OLIG2 has been shown in patients with precursor T-cell lymphoblastic lymphoma/leukemia (pre-T L...

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Detalhes bibliográficos
Main Authors: Lin, Ying-Wei, Deveney, Ramona, Barbara, Mary, Iscove, Norman N., Nimer, Stephen D., Slape, Christopher, Aplan, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1681523/
https://ncbi.nlm.nih.gov/pubmed/16103065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-05-1400
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