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Noise in transcription negative feedback loops: simulation and experimental analysis

Negative feedback loops have been invoked as a way to control and decrease transcriptional noise. Here, we have built three circuits to test the effect of negative feedback loops on transcriptional noise of an autoregulated gene encoding a transcription factor (TF) and a downstream gene (DG), regula...

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Bibliografske podrobnosti
Main Authors: Dublanche, Yann, Michalodimitrakis, Konstantinos, Kümmerer, Nico, Foglierini, Mathilde, Serrano, Luis
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1681513/
https://ncbi.nlm.nih.gov/pubmed/16883354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100081
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