Structure-activity relationships in the peptide antibiotic nisin: role of dehydroalanine 5.

A mutant of the peptide antibiotic nisin in which the dehydroalanine residue at position 5 has been replaced by an alanine has been produced and structurally characterized. It is shown to have activity very similar to that of wild-type nisin in inhibiting growth of Lactococcus lactis and Micrococcus...

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Detalhes bibliográficos

Publicado no:	Appl Environ Microbiol
Principais autores:	Chan, W C, Dodd, H M, Horn, N, Maclean, K, Lian, L Y, Bycroft, B W, Gasson, M J, Roberts, G C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC168084/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8702290/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.62.8.2966-2969.1996
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