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Isolation and expression in Escherichia coli of hepB and hepC, genes coding for the glycosaminoglycan-degrading enzymes heparinase II and heparinase III, respectively, from Flavobacterium heparinum.

Upon induction with heparin, Flavobacterium heparinum synthesizes and secretes into its periplasmic space heparinase I (EC 4.2.2.7), heparinase II, and heparinase III (heparitinase; EC 4.2.2.8). Heparinase I degrades heparin, and heparinase II degrades both heparin and heparan sulfate, while heparin...

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Dades bibliogràfiques
Publicat a:Appl Environ Microbiol
Autors principals: Su, H, Blain, F, Musil, R A, Zimmermann, J J, Gu, K, Bennett, D C
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC168057/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8702264/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.62.8.2723-2734.1996
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