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The central cytoplasmic loop of the major facilitator superfamily of transport proteins governs efficient membrane insertion

Deletion of 5 residues (Δ5) from the central cytoplasmic loop of the lactose permease of Escherichia coli has no significant effect on expression or activity, whereas Δ12 leads to increased rates of permease turnover after membrane insertion and decreased transport activity, and Δ20 abolishes insert...

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Bibliografiska uppgifter
Huvudupphovsmän: Weinglass, Adam B., Kaback, H. Ronald
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2000
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC16800/
https://ncbi.nlm.nih.gov/pubmed/10880570
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