The type III TGF-β receptor suppresses breast cancer progression

The TGF-β signaling pathway has a complex role in regulating mammary carcinogenesis. Here we demonstrate that the type III TGF-β receptor (TβRIII, or betaglycan), a ubiquitously expressed TGF-β coreceptor, regulated breast cancer progression and metastasis. Most human breast cancers lost TβRIII expr...

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Detalhes bibliográficos
Main Authors: Dong, Mei, How, Tam, Kirkbride, Kellye C., Gordon, Kelly J., Lee, Jason D., Hempel, Nadine, Kelly, Patrick, Moeller, Benjamin J., Marks, Jeffrey R., Blobe, Gerard C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1679965/
https://ncbi.nlm.nih.gov/pubmed/17160136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29293
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