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TIF1 Activates the Intra-S-Phase Checkpoint Response in the Diploid Micronucleus and Amitotic Polyploid Macronucleus of Tetrahymena

The ribosomal DNA origin binding protein Tif1p regulates the timing of rDNA replication and is required globally for proper S-phase progression and division of the Tetrahymena thermophila macronucleus. Here, we show that Tif1p safeguards chromosomes from DNA damage in the mitotic micronucleus and am...

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Autors principals: Yakisich, J. Sebastian, Sandoval, Pamela Y., Morrison, Tara L., Kapler, Geoffrey M.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1679683/
https://ncbi.nlm.nih.gov/pubmed/17005912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-05-0469
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