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A new role for a SNARE protein as a regulator of the Ypt7/Rab-dependent stage of docking

The homotypic fusion of yeast vacuoles occurs in an ordered cascade of priming, docking, and fusion. The linkage between these steps has so far remained unclear. We now report that Vam7p (the vacuolar SNAP-23/25 homolog) signals from the cis-SNARE complex to Ypt7p (the vacuolar Rab/Ypt) to initiate...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Ungermann, Christian, Price, Albert, Wickner, William
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16791/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10908678/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.160269997
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