Streptomyces-derived quorum-sensing systems engineered for adjustable transgene expression in mammalian cells and mice

Prokaryotic transcriptional regulatory elements have been adopted for controlled expression of cloned genes in mammalian cells and animals, the cornerstone for gene-function correlations, drug discovery, biopharmaceutical manufacturing as well as advanced gene therapy and tissue engineering. Many pr...

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Main Authors: Weber, Wilfried, Schoenmakers, Ronald, Spielmann, Manuela, El-Baba, Marie Daoud, Folcher, Marc, Keller, Bettina, Weber, Cornelia C., Link, Nils, van de Wetering, Petra, Heinzen, Christoph, Jolivet, Benoît, Séquin, Urs, Aubel, Dominique, Thompson, Charles J., Fussenegger, Martin
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2003
Teme:
NAR Methods Online
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC167645/
https://ncbi.nlm.nih.gov/pubmed/12853648
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