Stable High-Producer Cell Clone Expressing Virus-Like Particles of the Japanese Encephalitis Virus E Protein for a Second-Generation Subunit Vaccine

We produced and characterized a cell clone (J12#26 cells) that stably expresses Japanese encephalitis virus (JEV) cDNA, J12, which encodes the viral signal peptide, premembrane (prM), and envelope (E) proteins (amino acid positions 105 to 794). Rabbit kidney-derived RK13 cells were transfected with...

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Autors principals: Kojima, Asato, Yasuda, Atsushi, Asanuma, Hideki, Ishikawa, Toyokazu, Takamizawa, Akihisa, Yasui, Kotaro, Kurata, Takeshi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC167253/
https://ncbi.nlm.nih.gov/pubmed/12885894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.16.8745-8755.2003
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