Development of Recombinant Vesicular Stomatitis Viruses That Exploit Defects in Host Defense To Augment Specific Oncolytic Activity

Vesicular stomatitis virus (VSV) is a negative-stranded RNA virus normally sensitive to the antiviral actions of alpha/beta interferon (IFN-α/β). Recently, we reported that VSV replicates to high levels in many transformed cells due, in part, to susceptible cells harboring defects in the IFN system....

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Bibliografiset tiedot
Päätekijät: Obuchi, Masatsugu, Fernandez, Marilyn, Barber, Glen N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2003
Aiheet:
Gene Therapy
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC167243/
https://ncbi.nlm.nih.gov/pubmed/12885903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.16.8843-8856.2003
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