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PML Residue Lysine 160 Is Required for the Degradation of PML Induced by Herpes Simplex Virus Type 1 Regulatory Protein ICP0

During the early stages of herpes simplex virus type 1 (HSV-1) infection, viral immediate-early regulatory protein ICP0 localizes to and disrupts cellular nuclear structures known as PML nuclear bodies or ND10. These activities correlate with the functions of ICP0 in stimulating lytic infection and...

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Detalhes bibliográficos
Main Authors: Boutell, Chris, Orr, Anne, Everett, Roger D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC167235/
https://ncbi.nlm.nih.gov/pubmed/12885887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.16.8686-8694.2003
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