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Function of Herpes Simplex Virus Type 1 gD Mutants with Different Receptor-Binding Affinities in Virus Entry and Fusion

We have studied the receptor-specific function of four linker-insertion mutants of herpes simplex virus type 1 glycoprotein D (gD) representing each of the functional regions of gD. We used biosensor analysis to measure binding of the gD mutants to the receptors HVEM (HveA) and nectin-1 (HveC). One...

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Bibliografske podrobnosti
Main Authors: Milne, Richard S. B., Hanna, Sheri L., Rux, Ann H., Willis, Sharon H., Cohen, Gary H., Eisenberg, Roselyn J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC167229/
https://ncbi.nlm.nih.gov/pubmed/12885913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.16.8962-8972.2003
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