Induction of Protective Immune Responses against R5 Human Immunodeficiency Virus Type 1 (HIV-1) Infection in hu-PBL-SCID Mice by Intrasplenic Immunization with HIV-1-Pulsed Dendritic Cells: Possible Involvement of a Novel Factor of Human CD4(+) T-Cell Origin

The potential of a dendritic cell (DC)-based vaccine against human immunodeficiency virus type 1 (HIV-1) infection in humans was explored with SCID mice reconstituted with human peripheral blood mononuclear cells (PBMC). HIV-1-negative normal human PBMC were transplanted directly into the spleens of...

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Bibliographic Details
Main Authors: Yoshida, Atsushi, Tanaka, Reiko, Murakami, Tsutomu, Takahashi, Yoshiaki, Koyanagi, Yoshio, Nakamura, Masataka, Ito, Mamoru, Yamamoto, Naoki, Tanaka, Yuetsu
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC167224/
https://ncbi.nlm.nih.gov/pubmed/12885891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.16.8719-8728.2003
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