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Deletions in the Putative Cell Receptor-Binding Domain of Sindbis Virus Strain MRE16 E2 Glycoprotein Reduce Midgut Infectivity in Aedes aegypti

The Sindbis virus (Alphavirus; Togaviridae) strain MRE16 efficiently infects Aedes aegypti mosquitoes that ingest a blood meal containing 8 to 9 log(10) PFU of virus/ml. However, a small-plaque variant of this virus, MRE16sp, poorly infects mosquitoes after oral infection with an equivalent titer. T...

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Detalhes bibliográficos
Main Authors: Myles, Kevin M., Pierro, Dennis J., Olson, Ken E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC167217/
https://ncbi.nlm.nih.gov/pubmed/12885905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.16.8872-8881.2003
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