Cell Cycle Arrest by Kaposi's Sarcoma-Associated Herpesvirus Replication-Associated Protein Is Mediated at both the Transcriptional and Posttranslational Levels by Binding to CCAAT/Enhancer-Binding Protein α and p21(CIP-1)

Lytic-cycle replication of Kaposi's sarcoma-associated herpesvirus (KSHV) in PEL cells causes G(1) cell cycle arrest mediated by the virus-encoded replication-associated protein (RAP) (or K8 protein), which induces high-level expression of the cellular C/EBPα and p21 proteins. Here we have examined...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Wu, Frederick Y., Wang, Shizhen Emily, Tang, Qi-Qun, Fujimuro, Masahiro, Chiou, Chuang-Jiun, Zheng, Qizhi, Chen, Honglin, Hayward, S. Diane, Lane, M. Daniel, Hayward, Gary S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC167214/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12885907/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.16.8893-8914.2003
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