Potent, Persistent Induction and Modulation of Cellular Immune Responses in Rhesus Macaques Primed with Ad5hr-Simian Immunodeficiency Virus (SIV) env/rev, gag, and/or nef Vaccines and Boosted with SIV gp120

Immunity elicited by multicomponent vaccines delivered by replication-competent Ad5hr-simian immunodeficiency virus (SIV) recombinants was systematically investigated. Rhesus macaques were immunized mucosally at weeks 0 and 12 with Ad5hr-SIV(smH4) env/rev, with or without Ad5hr-SIV(mac239) gag or Ad...

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Main Authors: Patterson, L. Jean, Malkevitch, Nina, Pinczewski, Joel, Venzon, David, Lou, Yuanmei, Peng, Bo, Munch, Cindy, Leonard, Melissa, Richardson, Ersell, Aldrich, Kristine, Kalyanaraman, V. S., Pavlakis, George N., Robert-Guroff, Marjorie
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Vaccines and Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC167211/
https://ncbi.nlm.nih.gov/pubmed/12885879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.16.8607-8620.2003
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