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Inhibition of neuronal firing by opiates: evidence against the involvement of cyclic nucleotides.

1. Extracellular recordings were made in vitro from single neurones of the myenteric plexus of the guinea-pig ileum. 2. Neuronal firing was inhibited by morphine and normorphine (10 nM to 1 micrometer). Cyclic adenosine 3',5'-monophosphate (cyclic AMP) (100 micrometer to 1 mM) also inhibit...

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Detalhes bibliográficos
Main Authors: Karras, P J, North, R A
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1668673/
https://ncbi.nlm.nih.gov/pubmed/86371
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