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Ventilatory depression in naive and tolerant rats in relation to plasma morphine concentration

1 The disappearance of morphine from specially formulated pellets containing 75 mg morphine base was measured for 10 days after they were implanted into adult rats; the morphine content decreased at a rate of 5 mg pellet daily. 2 From the 2nd to the 6th day of implantation the plasma morphine concen...

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Bibliographic Details
Main Authors: Bowen, S.R., Carpenter, F.G., Sowell, J.G.
Format: Artigo
Language:Inglês
Published: 1979
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1668644/
https://ncbi.nlm.nih.gov/pubmed/427319
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