Inhibition of [3H]-dihydroalprenolol binding to rat cardiac membranes of various beta-blocking agents.

Binding of [3-H]-dihydroalprenolol ([3-H]-DHA) to rat cardiac membranes was rapid and reversible (k1 = 0.633-0.701 x 10(6) M(-1) S(-1) And k(-1) = 0.0017-0.0043 s(-1). 2 [3-H]-DHA bound to a single class of binding sites with an equilibrium dissociation constant (Kd25degreesc) of 5.7+/-1.1 x 10(-9)...

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Autores principales: Chenieux-Guicheney, P, Dausse, J P, Meyer, P, Schmitt, H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1978
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1668286/
https://ncbi.nlm.nih.gov/pubmed/25687
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