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Biochemical evidence for the dual action of labetalol on alpha- and beta-adrenoceptors.

1 Labetalol (AH 5158A) inhibited the adrenaline-stimulated adenylate cyclase activity of rat liver and heart. This drug had no effect on basal or guanosine triphosphate (GTP)-activated adenylate cyclase activities. 2 Labetalol displaced the binding of the specific ligands [3H]-dihydroergocryptine an...

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Bibliografske podrobnosti
Main Authors: Aggerbeck, M, Guellaen, G, Hanoune, J
Format: Artigo
Jezik:Inglês
Izdano: 1978
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1668053/
https://ncbi.nlm.nih.gov/pubmed/26446
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