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Plasma concentrations and cardiotoxic effects of desipramine and protriptyline in the rat

1 Desipramine and protriptyline were administered to anaesthetized rats by two consecutive intravenous infusions in order to obtain a peak level (first infusion) followed by lower steady state concentrations (second infusion) (Wagner, 1974). Theoretical plasma level time courses were confirmed exper...

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Bibliografiske detaljer
Main Authors: Bianchetti, G., Bonaccorsi, Aurora, Chiodaroli, A., Franco, R., Garattini, S., Gomeni, R., Morselli, P.L.
Format: Artigo
Sprog:Inglês
Udgivet: 1977
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1667180/
https://ncbi.nlm.nih.gov/pubmed/884382
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