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Compounds designed to fit a site of known structure in human haemoglobin.

1 The three-dimensional coordinates of the atoms in human haemoglobin are known, and there is a specific site in the deoxygenated form of the protein at which 2,3-diphosphoglycerate (DPG) interacts. 2 Molecular models of this site have been constructed and used to design compounds which should bind...

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Bibliografiske detaljer
Main Authors: Beddell, C R, Goodford, P J, Norrington, F E, Wilkinson, S, Wootton, R
Format: Artigo
Sprog:Inglês
Udgivet: 1976
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1667110/
https://ncbi.nlm.nih.gov/pubmed/938794
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