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The Drosophila Fragile X Protein dFMR1 Is Required During Early Embryogenesis for Pole Cell Formation and Rapid Nuclear Division Cycles

The FMR family of KH domain RNA-binding proteins is conserved from invertebrates to humans. In humans, inactivation of the X-linked FMR gene fragile X is the most common cause of mental retardation and leads to defects in neuronal architecture. While there are three FMR family members in humans, the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Deshpande, Girish, Calhoun, Gretchen, Schedl, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1667070/
https://ncbi.nlm.nih.gov/pubmed/16888325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.062414
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