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Accumulation of quinidine by human blood platelets: Effects on platelet ultrastructure and 5-hydroxytryptamine

1. We have studied the mechanism of quinidine uptake by normal human blood platelets. 2. Platelets in plasma or Krebs solution took up quinidine extremely rapidly, the maximal drug concentration ratio of platelet to medium being 24 to 1 after 1 minute. 3. The effects of metabolic inhibitors on uptak...

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Detalhes bibliográficos
Main Authors: Boullin, D. J., O'Brien, R. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1666999/
https://ncbi.nlm.nih.gov/pubmed/5580696
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