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Prediction of cytomegalovirus load and resistance patterns after antiviral chemotherapy
Cytomegalovirus (CMV) replicates rapidly in its human host with a doubling time of ≈ 1 day. Using simple mathematical models we show that the efficacy of the anti-CMV drug ganciclovir (GCV) against wild-type strains is 91.5% [95% confidence interval (CI) 89–94%] when given i.v. (5 mg/kg twice a day)...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The National Academy of Sciences
2000
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC16666/ https://ncbi.nlm.nih.gov/pubmed/10859361 |
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