Effect of morphine on adrenergic transmission in the mouse vas deferens. Assessment of agonist and antogonist potencies of narcotic analgesics.

1. Morphine inhibits the electrically evoked (0.1-0.15 Hz, 1 ms) contractions of the longitudinal muscle of the mouse vas deferens but not of the rabbit, guinea-pig, rat, cat, hamster or gerbil. This effect is stereospecific and is antagonized by naloxone or naltrexone. 2. Normorphine is equiactive...

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Bibliografiske detaljer
Main Authors: Hughes, J, Kosterlitz, H W, Leslie, F M
Format: Artigo
Sprog:Inglês
Udgivet: 1975
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1666422/
https://ncbi.nlm.nih.gov/pubmed/236796
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