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Inhibition of catecholamine uptake in the isolated rat heart by haloalkylamines related to phenoxybenzamine

1. Twenty-one haloalkylamine derivatives were tested as inhibitors of both the neuronal uptake of (3)H-noradrenaline (NA) by the Uptake(1) mechanism and the extraneuronal uptake of (3)H-NA by the Uptake(2) mechanism in the isolated rat heart. 2. At a concentration of 50 μM most of the compounds test...

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Autori principali: Iversen, L. L., Salt, P. J., Wilson, H. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1972
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1666366/
https://ncbi.nlm.nih.gov/pubmed/4676273
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