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Prostaglandin biosynthesis by human skin and its inhibition by corticosteroids

Homogenates of human breast skin form prostaglandins E(2) and F(2α) in the presence of arachidonic acid substrate. Significant inhibition of biosynthesis of prostaglandin E(2) and F(2α) was observed in the presence of the anti-inflammatory corticosteroid fluocinolone acetonide. This effect was dose-...

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Detalhes bibliográficos
Main Authors: Greaves, M. W., McDonald-Gibson, Wendy
Formato: Artigo
Idioma:Inglês
Publicado em: 1972
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1666109/
https://ncbi.nlm.nih.gov/pubmed/5084821
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