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Effect of cannabis and certain of its constituents on pentobarbitone sleeping time and phenazone metabolism

1. Cannabis extract prolonged sleeping time in mice in a thermally neutral environment (30-32° C) in which hypothermia does not occur. The prolongation was dose related, just detectable at 50 mg/kg, and 4-fold at 500 mg/kg. 2. Under these conditions, ether sleeping time was not prolonged. 3. Cannabi...

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Detalhes bibliográficos
Main Authors: Paton, W. D. M., Pertwee, R. G.
Formato: Artigo
Idioma:Inglês
Publicado em: 1972
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1666020/
https://ncbi.nlm.nih.gov/pubmed/4668592
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