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Excretion of (14)C-edrophonium and its metabolites in bile: Role of the liver cell and the peribiliary vascular plexus

1. The metabolism and biliary excretion of (14)C-edrophonium chloride was studied in Wistar rat. 2. Approximately 5% of the dose was recovered from bile in 6 hours. Most of the radioactivity was eliminated as (14)C-edrophonium glucuronide. Small amounts of the unchanged drug were also detected in bi...

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Autors principals: Back, D. J., Calvey, T. N.
Format: Artigo
Idioma:Inglês
Publicat: 1972
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665819/
https://ncbi.nlm.nih.gov/pubmed/5040663
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