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Destruction of chlorpromazine during absorption in the rat in vivo and in vitro

1. Concentrations of total radioactivity in plasma of rats given intravenous and oral (35)S-chlorpromazine, were similar. Concentrations of unchanged drug, however, were lower after oral doses. 2. Chlorpromazine circulated in solution through isolated loops of rat intestine was rapidly absorbed by t...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Curry, S. H., D'Mello, A., Mould, G. P.
Format: Artigo
Langue:Inglês
Publié: 1971
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665658/
https://ncbi.nlm.nih.gov/pubmed/5560899
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