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Whole-genome comparison of Leu3 binding in vitro and in vivo reveals the importance of nucleosome occupancy in target site selection

Sequence motifs that are potentially recognized by DNA-binding proteins occur far more often in genomic DNA than do observed in vivo protein–DNA interactions. To determine how chromatin influences the utilization of particular DNA-binding sites, we compared the in vivo genome-wide binding location o...

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Bibliografiske detaljer
Main Authors: Liu, Xiao, Lee, Cheol-Koo, Granek, Joshua A., Clarke, Neil D., Lieb, Jason D.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665635/
https://ncbi.nlm.nih.gov/pubmed/17053089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5655606
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