Drosophila NMNAT Maintains Neural Integrity Independent of Its NAD Synthesis Activity

Wallerian degeneration refers to a loss of the distal part of an axon after nerve injury. Wallerian degeneration slow (Wld(s)) mice overexpress a chimeric protein containing the NAD synthase NMNAT (nicotinamide mononucleotide adenylyltransferase 1) and exhibit a delay in axonal degeneration. Current...

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Autors principals: Zhai, R. Grace, Cao, Yu, Hiesinger, P. Robin, Zhou, Yi, Mehta, Sunil Q, Schulze, Karen L, Verstreken, Patrik, Bellen, Hugo J
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2006
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665629/
https://ncbi.nlm.nih.gov/pubmed/17132048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0040416
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