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Two phases of zymogen granule lifetime in mouse pancreas: ghost granules linger after exocytosis of contents

Different cell types show widely divergent mechanisms and kinetics of exocytosis. We investigated these processes in pancreatic acinar cells by using video-rate 2-photon microscopy to image entry of extracellular dye into individual zymogen granules undergoing exocytosis. Fluorescence signals displa...

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Detalles Bibliográficos
Main Authors: Thorn, Peter, Parker, Ian
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665585/
https://ncbi.nlm.nih.gov/pubmed/15637100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.077230
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